• 13.03.2019 Zakład Laboratoryjnej Diagnostyki Pediatrycznej

    Research & Science

     

    Research activity - the major research topics

     


    • Mechanisms of special immunity - lymphocyte subpopulation in different sickness states.
    • Immunological function of hypertrophied adenoid.
    • Complicity hypertrophied adenoid in pathophysiology otitis media with effusion.
    • Biological markers of alcohol abuse (sialic acid, CDT - carbohydrate-deficient transferrin)
    • Diagnostic usefulness of sialic acid and transferrin isoform profile in selected diseases

     

    Investigations methods
     

     

    • Flow cytometry
    • Electrochemiluminescence
    • Colorimetric biochemical methods
    • Immunoenzymatic methods
    • Cytochemistry staining
    • Fluorescence microscopy

     

    Publications
     

    • Gruszewska E., Cylwik B., Panasiuk A., Szmitkowski M., Flisiak R., Chrostek L.: Total and free serum sialic acid concentration in liver diseases. Biomed. Res. Int., 2014, doi.10.1155/2014/876096.
    • Chrostek L., Cylwik B., Gindzienska-Sieskiewicz E., Gruszewska E., Szmitkowski M., Sierakowski S.: Sialic acid level reflects the disturbances of glycosylation and acute-phase reaction in rheumatic diseases. Rheumatol. Int., 2014, 34, 393-399.
    • Cylwik B., Naklicki M., Chrostek L., Gruszewska E.: Congenital disorders of glycosylation. Part I. Defects of protein N-glycosylation. Acta Biochim Pol., 2013, 60, 151-161.
    • Cylwik B., Lipartowska K., Chrostek L., Gruszewska E.: Congenital disorders of glycosylation. Part II. Defects of protein O-glycosylation. Acta Biochim Pol., 2013, 60, 1-11.
    • Cylwik B, Naklicki M, Gruszewska E, Szmitkowski M, Chrostek L. The distribution of serum folate concentration and red blood cell indices in alcoholics. J Nutr Sci Vitaminol., 2013, 59, 1-8.

    • Gruszewska E., Chrostek L., Cylwik B., Tobolczyk J., Szmitkowski M., Kukliński A., Kędra B.: Serum sialic acid as a merker of pancreatic cancers. Clin Lab., 2013, 59, 781-788.

    • Żelazowska-Rutkowska B., Wysocka J., Ratomski K., Kasprzycka .E, Skotnicka B.: Increased percentage of T cells with the expression of CD127 and CD132 in hypertrophic adenoid in children with otitis media with effusion.Eur Arch Otorhinolaryngol., 2012, 269, 1821-1825.

    • Żelazowska-Rutkowska B., Iłendo E., Skotnicka B., Wysocka .J, Kasprzycka E.: Production of cytokines by mononuclear cells of hypertrophic adenoids in children with otitis media with effusion.Folia Histochem Cytobiol., 2012,50:586-589.

    • Krawczuk-Rybak M., Leszczyńska E., Poznańska M., Żelazowska-Rutkowska B., Wysocka J.: The progressive reduction in the ovarian reserve in young women after anticancer treatment. Horm Metab Res., 2013, 45, 813-819.