LECTURES

1. Introduction to the immune system. Types of immune responses. Innate immunity.

2. Specific immune response: cellular and humoral. Antigen presentation.

3. Hypersensitivity reactions.

4. Anti-infective immunity. Active and passive immunoprophylaxis.

5. Tolerance and autoimmunity. Autoimmune diseases. TEST

6. Fundamentals of transplant immunology, donor and recipient selection.

7. Blood group systems: ABO and Rh. Serological incompatibility.

8. Cancer immunology. Immunotherapy. Immunomodulation.

9. Primary and secondary immunodeficiencies.

10. Immunology of the neonatal and pediatric period, age-related changes. TEST

SEMINARS

1. Where immunity begins – mucosal immunology in practice
2. The Immune System’s GPS – How Do Leukocytes Know Where to Go?
3. Behind the Scenes of Immunity: The Cytokine Story
4. From Alarm to Resolution: The Biology of Inflammation, Repair and Regeneration Processes
5. The Immune Puzzle: Identifying Deficiencies and Dysfunctions

CLASSES

1. Immune system cells. Basic panels in immunological diagnostics.
   Practical part – evaluation and interpretation of results:

• WBC (white blood cell count)

• Leukogram

2. Diagnostics of disorders in the number and/or function of innate immune response cells.
   Practical part – evaluation and interpretation of results:

• Latex phagocytosis test

• NBT (Nitroblue Tetrazolium) test

3. Diagnostics of disorders in the number and/or function of lymphocytes.
   Practical part – evaluation and interpretation of results:

• Lymphocyte subpopulation phenotyping by flow cytometry

• Blast transformation test

4. Diagnostics of humoral immune response: complement system, antibodies, cytokines.
   Practical part – evaluation and interpretation of results:

• CH50 test

• Immunoglobulin concentration measurement

5. Serological diagnostics of blood groups and maternal-fetal incompatibility in the ABO and Rh systems.
   Practical part – evaluation and interpretation of results:

• Determination of ABO blood groups and RhD antigen using slide and column methods