Name of a course / module

Pathomorphology

Name of a department where course is held

Department of Medical Pathomorphology Medical University of Bialystok

E-mail of department

patlek@umb.edu.pl

Faculty of

Medicine with Division of Dentistry and Division of Medical Education in English

Name of a field of study

Faculty of medicine

Level of education

First degree studies, Uniform master’s degree studies

Form of study

full time ⬜                                 part time ⬜

Language of instruction

Polish  ⬜                                 English ⬜

Type of course

obligatory ⬜                                 facultative ⬜

Year of study / Semester

I ⬜   II ⬜   III ⬜   IV ⬜   V ⬜  VI ⬜

1 ⬜   2 ⬜   3 ⬜   4 ⬜   5 ⬜   6 ⬜   7 ⬜   8 ⬜   10 ⬜

11 ⬜   12 ⬜

Introductory courses with preliminary requirements

Anatomy, histology, physiology, pathophysiology, biochemistry, laboratory medicine

Students ought to have the basic knowledge of anatomy and histology of human tissues. Student must understand the basics of human physiology in order to understand the mechanisms of disease. Students should have a basic knowledge of basic pathomechanisms of disease entities, in order to correlate them with the histopathologic picture. In correlation with the basics of pathophysiology, laboratory medicine student  is able to learn the material in the field of pathology.

Number of didactic hours with specification of forms of conducting classes

II year 35 lectures,75 labs

III year 20 lectures, 45 labs

Assumptions and aims

of the course

Students are obligated to possess the knowledge about: basic pathomorhologic nomenclature, basic mechanisms and morphology about cell death, cell injury, adaptive processes, hemodynamic disorders, basic definitions associated with acute and chronic inflammation. Student ought to know intrinsic and extrinsic pathogens , immunological reactions, molecular alterations associated  with carcinogenesis, neoplasms and diseases of childhood.

Student must know all of the morphological changes associated with the diseases, must be able to merge changes with the diseases and clinical trials, and must have the basic knowledge about systemic pathology, diseases of organ systems:

1.        Blood Vessels

2.        The Heart

3.        Diseases of White Blood Cells, Lymph Nodes, Spleen, and Thymus

4.        Red Blood Cell and Bleeding Disorders

5.        The Lung and upper respiratory tract

6.        Head and Neck

7.        The Gastrointestinal Tract

8.        Liver and Biliary Tract

9.        The Pancreas

10.        The Kidney

11.        The Lower Urinary Tract and Male Genital System

12.        The Female Genital Tract

13.         The Breast

14.        The Endocrine System

15.         The Skin

16.        Bones, Joints, and Soft Tissue Tumors

17.        Peripheral Nerve and Skeletal Muscle

18.        The Central Nervous System and Eye

Didactic methods

- lectures

- consultation (both regular and organized in individual cases)

- discussion during the labs

- slides presentations

- Slides watching (students try to diagnose the histopathological slides under the microscope and do the differential diagnosis)

- case description

- self study

- study of the literature

- other practical classes (electives, grossing, autopsy, intraoperative diagnosis, fine needle biopsy)

Full name of the person conducting the course

employed scientific and teaching Staff

Full name of the person responsible for teaching

Grzegorz Zalewski MD, PhD

Symbol and number of learning outcomes according to the teaching standards and other learning outcomes

Description of directional learning outcomes

Form of classes

Verification methods  for achieving intended learning outcomes

Knowledge

C.W25

C.W26

CW27

CW28

CW29

CW30

CW31

CW32

Pathomorhological terminology

Basic mechanisms of cell and tissue damage

Clinical course of specific and unspecific inflammation, regeneration processes of organs and tissues

Definition and pathophysiology of the shock, especially various causes of shock and multiorgan failure

Etiology of hemodynamic disorders, progressive and retrogressive changes

Problems of an organ pathology, macro-and microscopic images and clinical course of pathomorphological lesions in the organ

Consequences of process of pathologic changes for adjoining organs

Internal and external pathogenic factors and modifiable and unmodifiable ones

Labs, seminaries

- observation of the student's work

- evaluation of the activity in the classroom

- assessment of preparation for classes

- discussion in class

- partial tests

- preliminary tests

- case description

- final exam- test

Skills

DU6

DU11

DU12

DU15

DU17

Students should acquire the skills about:

1.        method of securing material for histopathological research

2.        choosing the most proper method for specimen evaluation (histopathological evaluation, cytological, oligobiopsy, intraoperative examination)

3.        Macroscopic evaluation of the material (grossing)

4.        ability to efficiently microscopy and the diagnosis of basic morphological disorders

5.        ability to perform differential diagnosis

6.        enforcement of section essential organs

Labs, seminaries

- observation of the student's work

- evaluation of the activity in the classroom

- assessment of preparation

for classes

- discussion in class

- partial tests

- case description

Social competence

He /She recognizes his/her own  diagnostic and therapeutic limitations,  educational needs, planning of educational activity

He /She is able to work in a team of professionals, in a multicultural and multinational environment

He /She implements the principles of professional camaraderie and cooperation with representatives of other professionals in the range of health care

He /She observes doctor-patient privilege; and patient rights

Labs, seminaries

Summarizing methods e.g.,

Continuous assessment by teachers (observation)

Forming methods, e.g.,

- observation of the student's work

- discussion in class

- opinions of patients, colleagues

ECTS points

Należy podać liczbę punktów ECTS przypisaną przedmiotowi.

Student Workload

Form of activity

Number of hours to complete the activity

Classes that require the participation of a teacher

1.  Realization of the course: lectures (according to the curriculum )

55 (15 IIED, 40 IIIED)

2. Realization of the course: classes (according to the curriculum )

120  (30 IIED, 90 IIIED)

3. Realization of the course: seminars; (according to the curriculum)

0

4. Realization of the course: electives

0

5. Participation in consultation

Total hours: 175

Student self-study

1 punkt ECTS oznacza 25-30 godzin pracy studenta w różnych formach, takich jak np.:

1. Preparation for the theoretical and practical classes (realization of projects, documentation, case description etc.)

25 hours (1 ECTS)

2. Preparation for tests/credits

50 hours (2 ECTS)

3. Preparation for an exam/final test-credit

50 Hours (2 ECTS)

Total hours: 125 hours

Course contents:

Learning outcomes

(symbol and number)

Topics

C.W25

C.W26

CW27

CW28

CW29

CW30

CW31

CW32

DU6

DU11

DU12

DU15

DU17

Cellular adaptations, cel injury and death

Acute and chronic inflammation

Tissue renewal and repair, regeneration, healing, and fibrosis

Hemodynamic disorders, thromboembolic disease and shock

Genetic disorders, environmental and nutritional pathology

Diseased and neoplasms of infancy and childhood

Diseases of blood vessels and heart

Hematopoietic system pathology, non-Hodgkin and Hodgkin lymphomas, pathology of thymus and spleen

The upper air tract pathology, lung diseases, lung tumors

The gastrointestinal tract pathology

Liver and biliary tract diseases and neoplasms

Inflammatory diseases of pancreas and neoplasms

Kidney pathology- glomerulonephritis, interstitial diseases, inflammation, neoplasms

The lower urinary tract pathology and male genital system diseases and neoplasms

The female genital tract pathology

Breast pathology, breast cancer- etiology, predictive and prognostic features

The endocrine system pathology, most common endocrine system syndromes

Skin pathology

Bone, joints pathology, and soft tissue tumors

The central and peripheral nervous system pathology, including eye pathology

Obligatory textbook: (1-2 pozycje)

“Robbins and Cotran Pathologic basis of disease”, 10th edition

Optional textbook: (1-2 pozycje)

Klatt EC. “Robbins and Cotran Atlas of Pathology”

Emmanuel Rubin, David S. Strayer, Jeffrey E. Saffitz. “Rubin's Pathology: Mechanisms of Human Disease”

Criteria for assessing the achieved learning outcomes and the form and conditions for receiving credit: Należy określić w szczególności: zasady dopuszczenia do egzaminu, zwalniania z egzaminu, sposób i warunki zaliczenia zajęć, łącznie z określeniem zasad zaliczania nieobecności oraz określeniem liczby godzin nieobecności kwalifikujących do niezaliczenia przedmiotu oraz możliwości i formy wyrównywania zaległości

Throughout the course, students’ knowledge is evaluated via partial credits (tests) administered according to the published schedule.

*Each credit consists of 30 text-based multiple-choice questions and/or slide-based questions (from the online library: http://library.med.utah.edu/WebPath/ORGAN.html ).

*Each test carries a maximum of 30 points.

*Attendance at all partial credits is mandatory. Tests cannot be taken on alternative dates, except in cases of justified absence.In such cases, students must contact the course coordinator to arrange an additional term at the end of the semester.

*All credits are conducted as scheduled in the lecture room and last 30–40 minutes.

*Results are announced within one week via Blackboard.

*Students have the right to review their answer sheets during the week following the announcement of the results.

To pass the semester, the student must:

Attend laboratory classes as required.

Obtain at least 55% of the total available points for that semester.

At the end of each semester, students who fail to obtain the required number of points may take a midterm exam, consisting of  multiple-choice questions covering that semester’s material.

A score of 55% is required to pass.

Students who fail the midterm will be required to take an oral semester exam with the Head of the Department.

FINAL EXAMINATION

*The final exam (first term) is scheduled during the winter examination session and consists of 120 multiple-choice questions, including 15–20 image-based questions (from the same online library).

*Each correct answer is worth 1 point.

*The minimum passing score is 60% (72 points), but it may be moderately reduced if statistical analysis of the results (Gaussian distribution) indicates an unusually high level of difficulty.

*Bonus points are awarded for high attendance (>90%) and performance during the semester (excluding midterms):

Semester Performance        Bonus Points

≥60% of points        +1 pts

≥70% of points        +2 pts

≥80% of points        +3 pts

≥90% of points        +5 pts

The retake exam (second term) takes place not earlier then in 2 weeks and has the same format as the original test.

*Grading scale for the final exam:

Grade        Description        Percentage

5.0        Very good        95–100%

4.5        Better than good        90–94%

4.0        Good        84–89%

3.5        Satisfactory        73–83%

3.0        Pass        60–72%

2.0        Unsatisfactory / Fail        0–59%

Absence from the final exam must be excused no later than the day of the exam.

Unexcused absence results in a fail grade (2.0) for that term.