• Updated 24.06.2020 by Zakładu Medycyny Regeneracyjnej i Immunoregulacji







    Academic year 2019/2020


    Name of a course / module

    Regenerative Medicine

    Name of a department where course is held

    Department of Regenerative Medicine and Immune Regulation

    E-mail of department


    Faculty of

    Medicine with Division of Dentistry and Division of Medical Education in English

    Name of a field of study


    Level of education

    Uniform master’s degree studies

    Form of study

    full time ¢ part time £

    Language of instruction

    Polish £ English ¢

    Type of course

    obligatory ¢ facultative £

    Year of study / Semester


    I £ II ¢ III £ IV £ V £ VI £



    1 £ 2 £ 3 ¢ 4 £ 5 £ 6 £ 7 £ 8 £ 10 £

    11 £ 12 £


    Introductory courses with preliminary requirements

    Student should obtain obligatory credit of biophysics, chemistry, biochemistry and histology, cytophysiology and embryology.


    Number of didactic hours with specification of forms of conducting classes

    Lectures: 10

    Classes: 5

    Assumptions and aims

    of the course

    Upon completion of the course students will get the knowledge in:

    1. Basic principles of regeneration, healing and aging.

    2. Laboratory research in the field of regenerative medicine and it’s clinical applications.

    3. How to utilize basic laboratory technics and to plan simple experiments.

    Didactic methods


    - lectures with a discussion,

    - consultation (group or individual for the request of the students),

    - self-study,

    - other practical classes (observations, individual experiments),

    - presentation of an experiment carried out during the classes


    Full name of the person conducting the course

    Dawid Groth, MD

    Full name of the person responsible for teaching

    Professor Marcin Moniuszko, MD, PhD


    Symbol and number of learning outcomes according to the teaching standards and other learning outcomes

    Description of directional learning outcomes

    Form of classes

    Verification methods for achieving intended learning outcomes



    Knows the mechanisms of cell-cell and cell-extracellular matrix interactions, but also intracellular signaling pathways and examples of disorders in these processes


    Summarizing methods:

    - written final test

    Forming methods:

    - observation of the student's work

    - evaluation of the activity in the classroom

    - assessment of preparation for classes

    - discussion in class



    Knows the processes: cell cycle, proliferation, differentiation, aging, apoptosis, necrosis and their functions in human body




    Knows the basics of stem cells and their clinical applications



    Knows the mechanisms of aging



    Knows the basics of research (observations, experiments, in vitro), which may lead to the development of medicine



    Knows the basic definitions in genetics



    Knows the basics of disinfection, sterilization and aseptic work



    Knows the basic mechanisms of cell and tissue injury



    Describes clinical course of innate and adaptive immune responses, but also describes processes of tissue and organ regeneration




    Knows how to plan and carry out an experiment and how to obtain results and draw a conclusion


    Summarizing methods:

    - realization of a specific task

    - project, presentation


    Forming methods:

    - observation of the student's work

    - evaluation of the activity in the classroom

    - completion of each activity

    - discussion in class

    - presentation


    Social competence


    be aware of his/her own limitations and need to improve their skills continually


    Summarizing methods:

    Continuous assessment by teachers (observation)

    Forming methods:

    - observation of the student's work

    - discussion in class

    - opinions of colleagues



    ECTS points


    Student Workload

    Form of activity

    Number of hours to complete the activity

    Classes that require the participation of a teacher:

    1. Realization of the course: lectures (according to the curriculum)


    1. Realization of the course: classes (according to the curriculum)


    1. Realization of the course: seminars; (according to the curriculum)


    1. Realization of the course: electives


    1. Participation in consultation



    Total hours: 15

    Student self-study:

    1 punkt ECTS oznacza 25-30 godzin pracy studenta w różnych formach, takich jak np.:

    1. Preparation for the theoretical and practical classes (realization of projects, documentation, case description etc.)


    1. Preparation for tests/credits


    1. Preparation for an exam/final test-credit



    Total hours: 30




    Course contents:

    Learning outcomes

    (symbol and number)


    1. B.W23.; B.W28.; B.W34.; C.W1.; B.U14.;

    2. B.W23.; B.W28.; C.W1.; C.W27.;

    3. B.W21.; B.W23.;

    4. B.W21.; B.W22; C.W1;


    5. B.W21.; B.W22.; B.W28; C.W1; B.U14.;


    6. B.W21.: B.W22.; B.W34.; C.W19.; C.W26.; B.U14.;

    7. C.W26.; C.W27.;

    8. B.W21; B.W22; B.W23.; C.W19.; C.W26; C.W27.;

    9. B.W34.; B.U14.;

    10. B.W21.; B.W22.; B.W23.; B.W28.; C.W1.; C.W26.; C.W27; B.U14.;

    11. B.W21.; B.W22.; B.W23.; B.W28.; B.W34.; C.W1.; C.W19.; C.W26.; C.W27.; B.U14., B.U14.;

    1. Regenerative medicine – principles and ethics.

    2. Progenitor and stem cells – characteristics.

    3. Intra- and extracellular matrix.

    4. Transcription factors, signaling proteins and cell-surface receptors – principles and functions.

    5. Regulation of cells’ differentiation and proliferation.


    6. Mechanisms of cell’s death and it’s consequences.

    7. Processes which lead to injury of cells and tissues.

    8. Healing and regeneration – mechanisms and differences.

    9. Principles of carrying out a research.

    10. Mechanisms of tissue and organ regeneration;


    11. Principles of cell-based and biological therapy.




    Obligatory textbook:

    1. Knowledge obtained during the lectures and classes.

    Optional textbook:

    1. Anthony Atala, Robert Lanza, James A. Thomson, and Robert M. Nerem; Principles of Regenerative Medicine
    2. Robert A. Brown; Extreme Tissue Engineering


    Criteria for assessing the achieved learning outcomes and the form and conditions for receiving credit:

    Student obtains a credit on condition that he/she was present on all lectures and classes and obtained a pass from the classes.


    Students are obliged to attend all classes. Absences should be excused as soon as possible. In case of illness, a doctor’s leave should be presented; any other absences should be confirmed by the dean or proper authorities. Excused absences should be make up in a fixed time. The consequence of unexcused absences (more than one) is lack for credit at Regenerative medicine.


    The conditions of passing the class:

    a) performing experiments with showing an understanding of a sense of carried procedures;

    b) presentation of the experiment during the last classes

    b) credit from a written partial class test.


    During the last class every student is obliged to present an evaluation of their experiment, which was carried out on the laboratory classes. Every student may obtain maximum 10 points – 2 points for each of the following: introduction, material and methods, results, conclusion and student’s contribution to the presentation. The minimum 6 points are required to pass the presentation. Passing the presentation is mandatory in order to pass the course of Regenerative Medicine