PhD First year Project: Decoding the mechanism of Ceragenins action against bacterial and fungal cells.
The project aims to provide an in-depth understanding of the molecular mechanism of action of Ceragenins at the gene expression level that will further lead to optimization of therapeutic applications and future design of antimicrobial agents. Various group of genes along with their regulators such as efflux pumps, stress response pathways, outer membrane lipid biosynthesis and mitochondrial ROS stress genes are involved in the microbial defence mechanisms and their expressions are particularly induced by antimicrobial agents. We will focus on studying the relationship between the genotypic and phenotypic properties of the treated organisms.
Department of Medical Microbiology and Nanobiological Engineering
Supervisor: Prof. Robert Bucki, PhD
Co-investigators: Krzysztof Fiedoruk, MD-PhD
Ewelina Piktel, MD-PhD
Piotr Deptuła, D.Eng.
Bachelor of Science in Medical Biotechnology
Thesis Project - Association of leptin receptor gene variation with obesity and diabetes induced cardiovascular diseases - A pilot study
Master of Science in Medical Biotechnology
Thesis Project - Development of an optimal method of miRNA isolation: A comparative study
Genomics, Molecular Biology, Microbiology, Cell culture