PhD students will be involved in research projects aimed at lipidomic and metabolomic approaches in pathologies connected with oxidative stress generation. The studies will cover dependencies between phospholipid peroxidation and enzymatic metabolism in skin injuries in the context of redox imbalance and inflammation. The changes in the cross-talk between products of phospholipid metabolism and antioxidants at protein and transcriptional level in pathologies will be explored. The research will include lipidomics and proteomics fingerprinting analysis of body fluids, tissues homogenates or cell cultures as well as target - quantitative analysis of particular compounds examined as potential biomarkers. During the project implementation, PhD students will use advanced analytical and biochemical techniques including LCMSMS (QTOF, QTRAP, and QQQ), GSMSMS (QQQ), GCGCMS, Western Blotting, ELISA, in vitro cell cultures.
MUB Expert: professor Elżbieta Skrzydlewska