Project 2020: Determination of diabetes polygenic risk scores in discriminating phenotypic sub-spaces.
Principal Investigator's Supervisor: Prof. Dr hab. Adam Kretowski and Dr hab. Miroslaw Kwasniewski
Name of the department, where the project will be carried out: Center for Bioinformatics and Data Analysis, and Clinical Research Center.
Abstract. Diabetes is the fastest growing disease in the world. Evidence suggests that early treatment is crucial for prevention of complications in the patients. The number of studies combining phenotypic and genetic variables to predict the diabetes risk increases as showing generally promising results. The polygenic risk scores are encouraging decision support for diagnosis and they are reliable when it comes to discriminate diabetes subtypes. A refined classification of diabetes subtypes merging phenotypic features and polygenic risk scores to stratify, could provide a powerful tool to individualize treatment regimens and identify individuals with increased risk of complication at diagnosis, defining a kickoff towards precision medicine in diabetes.
Background: Biology, Molecular Biology, Biotechnology, Medical Pharmaceutical, Bioinformatics.
Biography. ¡Hola! I’m Luis Felipe Padilla-Martínez, from Guanajuato, México. I studied the bachelor in Experimental Biology in the University of Guanajuato, graduated in 2015. During my bachelor I made a stay in The University of Arizona, completing the Latin American Summer Research Program. In 2015 I was accepted to do my Master’s degree in the Center for Research and Assistance in Technology and Design of the State of Jalisco AC (CIATEJ), in the area of Medical Pharmaceutical Biotechnology. I made a research stay during my master degree at the Autonomous University of Barcelona, in the institute of biotechnology and biomedicine where I learned to use bioinformatics tools for genomic analysis.
Right now I’m a PhD second year student enrolled in the “ImPRESS HORIZON 2020 cofund doctoral program” held at the Medical University of Białystok.