Project: Complete pharmacogenomics profiling of individuals, new insight for the future of personalized drug therapy
Main project overview
We, in the Department of Analysis and Bioanalysis of Medicines, plus the Clinical Research Center of the Department of Endocrinology, Diabetology and Internal Medicine, are going to perform one of the most comprehensive pharmacogenomics studies in Poland.
The main efforts would be the complete pharmacogenomics profiling of individuals, using the high throughput sequencing (next generation sequencing) methods in order to reveal the specific functional genetic variants, which are responsible for different drug metabolism in different patients or even healthy individuals.
As we are going to genotype most of pharmacogenes in the human body at three separate levels, this project could be considered as a large scale analysis of the genome. As most of the previous researches in the field, focused on some specific genes or drugs, which showed the priority for the definite area but here, at Bialystok, Poland in the Euroregional center of pharmacy in collaboration to other well-known centers around the Europe, we decided to perform an advanced and comprehensive clinical pharmacology and pharmacogenomics project, which is an absolute approach toward the personalized medicine.
1. Alireza Tafazoli (Principal Investigator)
2. Prof. Wojciech Miltyk and Prof. Adam Krętowski (Principal Investigator’s Supervisors)
3. Magdalena Niemira, Ph.D. (other investigators)
4. Anna Szałkowska, mgr (other investigators)
5. Witold Bauer, mgr (other investigators)
6. Prof. Karol Kaminski, Ph.D. (other investigators)
7. Renata Posmyk, MD, Ph.D. (other investigators)
8. Natalia Wawusiewicz-Kurylonek, Ph.D. (other investigators
• Medical/Human Genetics and Genomics (variant analysis)
• Pharmacogenetics and Pharmacogenomics
• Next Generation Sequencing
More information about me you can find on my Google Scholar website